The first "American Corner " in Indonesia was inaugurated by U.S. Ambassador Ralph L. Boyce and Rector Prof. Dr. Azyumardi Azra on Thursday, March 18, 2004 at the Islamic State University (UIN) Syarif Hidayatullah, Ciputat, Jakarta. The Second "American Corner " was also inaugurated by U.S. Public Affairs Counselor, Charles N. Silver and UMY Rector  Dr. Khorudin Bashori on Saturday, April 24, 2004 at the Universitas Muhammadiyah Yogyakarta (UMY) ,Yogyakarta, Central Java. 

Another American Corners which already in operation were American Corner at Universitas Airlangga (UNAIR) Surabaya, Universitas Gadjah Mada (UGM) and Universitas Muhammadiyah Malang (UMM).  The first  "American Corner" in Sumatra, AC-IAIN Sumatra Utara (IAIN SU) Medan,  was opened by Deputy Chief of Mission (DCM) Lewis Amselem and IAIN SU Rector Prof. Dr. H.M. Yasir Nasution to the general public at Wednesday, September 22, 2004 at the Insitut Agama Islam Negeri (IAIN) Sumatra Utara, Medan, AC IAIN Walisongo Semarang on last January 2005. 

Rector Universitas Indonesia, UI Rector Prof. Usman Chatib Warsa, and Deputy Chief of Mission, US Embassy, Lewis Emselem delivered opening speech on the inauguration of American Corner UI Jakarta on Wednesday, February 24. 2005. American Corner UI is the eighth American Corner to open in Indonesia and the second in Jakarta.

On September 2005, American Corner Universitas Hasanuddin (UNHAS), Makassar, South Sulawesi was officially innaugurated by  Deputy Chief of Mission (DCM) Lewis Amselem and UNHAS Rector, Prof Ir. Rady A. Gani. And the latest one, American Corner  University of North Sumatra (USU), Medan opened on December 2005.

The first American Corner for Bandung area was officially opened by Rector Prof. Djoko Santoso and Deputy Chief of Mission of the U.S. Embassy, John Heffern on February 19, 2008. The American Corner ITB is the 11th American Corner in Indonesia, and the only American Corner in Indonesia which is located in Science and Engineering University

"American Corners" are partnerships between United States Embassies and host institutions. They provide access to current and reliable information about the United States through book and magazines collections, the Internet, CD-ROMs. DVDs, On-line Database, and programming. The first American Corner opened in Russia in October 2000. Since that time, over 60 countries in Europe, Asia and Africa have become part of the growing network of American Corners across the globe.

The U.S. Embassy in Jakarta will establish eleven "American Corners" over the coming year in selected locations in Indonesia to promote understanding of the United States, its culture, history and policies. These are formal partnerships between the U.S. Embassy and Indonesian universities.

The American Corners is a true partnership. The United States Embassy has provided the books and equipment needed to set up the Corner; The host institution is providing the space and the staff to make the Corner work.

Each American Corner features a diverse collection of English language books and materials about the United States and is similar to a university library reference service. All the American Corners will be staffed by bilingual Indonesian library personnel who will be available during regular library hours to assist patrons interested in specific information about the United States.

The collection includes reference books, works of fiction, and commercial and government publications. Each American Corner also features computers with guided Internet access, as well as audio and video materials and CD-ROMS. The collection's design includes support for information on English language instruction. Each American Corner also provides resources about doing business in the United States.

In addition, each American Corner in Indonesia will offer public programs to make information about the United States available to the Indonesian public. For example, other American Corners have hosted speakers, workshops and meetings and served as a venue for locally-generated programs such as an American film series, English classes, or educational advising.